PTSD — Seeking the Ghost in the Machine | NEJM – nejm.org

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A century after “the war to end all wars,” we continue to find our human community divided by conflict and our military service members at the leading edge. The ghostly scars of shell shock, later termed post-traumatic stress disorder (PTSD), have haunted generations of soldiers, as well as civilian survivors of many types of trauma, since long before the Great War. Despite current societal acceptance of PTSD as a disorder worthy of compassion, diagnostic recognition, and multidisciplinary research, these scars have remained, like ghosts, largely and frustratingly invisible in the sense that little is understood of their cellular basis in . . .

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